Oriel Medical Devices Ltd has designed and developed an instrument which is truly portable and utilises a closed loop system which accurately regulates the temperature of coolant for patients who suffer from medical conditions such as:
This product also overcomes the disadvantages of the hospital based systems which may be invasive; require trained medical staff and access to mains power
The system permits the heating as well as the cooling of the liquid in the closed loop. This can be important when using different attachments for different applications.
To improve patient prognosis following medical conditions such as heart attacks, strokes, head trauma, birth defects, etc… there is a significant consensus amongst the medical profession that early intervention to cool the brain is greatly beneficial.
Induced hypothermia is commonly used to cool the patients body temperature in order to achieve the improvements in prognosis.
In addition, it is known that for patient's undergoing treatments for cancers, cooling the head may ease the discomfort and assist in the retention of hair. However, present methods are generally invasive and involve whole body cooling. Cooling methods are generally restricted to a hospital environment and have potential risks to other body organs. Furthermore, many of the techniques used involve liquid coolant being introduced through nasal passages.
It has also been suggested that the system may be adapted to provide the more efficient and reliable transport of body organs for transplant purposes. The organs may be transported within the desired temperature range and then warmed to the appropriate temperature prior to transplant
The photograph shows the "patient" with the headset fitted & held in position with a chin strap to ensure good thermal contact on the patient's head.
The advantages of imrt for bone marrow sparing compared with conventional techniques have been shown. (11,14) in recent analyses, it was shown that the volume of pelvic bone marrow (pbm) and lumbosacral bone marrow (lsbm) receiving 10 and 20 gy are significantly associated with acute ht events in patients undergoing concurrent chemotherapy and imrt. (15â€“16) therefore, search for techniques to further minimize the low doses (in the range of 10â€“20 gy) to pbm seems logical. One potential modality that may be able to do this is protons. (17,18) with its attractive physical characteristics (e. G. cheap generic viagra , low entrance dose, spread-out bragg peak, and finite particle range), proton therapy can potentially reduce the dose to pbm more so than imrt. online prescription viagra In fact, a number of investigators looked into the potential use of protons for cervical cancer treatments and concluded that doses to organs at risk (oars) are reduced. cheap generic overnight viagra (19â€“22) however, none have looked at pbm sparing specifically. The purpose of this study was to compare imrt with three-dimensional conformal proton therapy (3dcpt) for dosimetric benefits in the treatment of cervical cancer. In particular, each techniqueâ€™s ability to spare pbm was of primary interest in this study. To do this, we developed treatment plans using imrt and proton therapy specifically designed to maximize the bone marrow sparing (bms) intent. The dose-volume histograms (dvh) were the main means of comparison. Ii. low cost generic viagra Materials and methods a. Simulation six cervical cancer patients (3 postoperative and 3 intact) treated at the university of california, san diego (ucsd) were selected for analysis. All patients were immobilized with customized vac loc bags encompassing the upper and lower body before a ct scan of the pelvic region was performed (ge wide-bore 4-slice lightspeed ct scanner, ge healthcare, usa). viagra pills for sale Oral, intravenous and rectal contrasts were administered in select patients to aid in the delineation of normal and target tissues. B. Volume definition following icru 50 and 78 recommendations,(23,24) the clinical target volume (ctv) and oar structures were contoured on individual simulation ct studies. Detailed description of the delineations can be found in previous publications. (10,12) in brief, the ctv consisted of the pelvic and presacral lymph nodes, uterus and cervix (if present), upper vagina, and parametrial tissues. Oars included bowel, rectum, bladder and pbm (including lumbosacral spine, os coxae, and proximal femora). cheap generic viagra The overall ptv and pbm volumes were 1035. 9 â± 192. sales of viagra 2 cm 3 and 1151. 4 â± 198. 3 cm 3 , respectively. All plans had uniform 1. buy discounted viagra 0 cm ctv-ptv margin and were normalized to cover the 95% ptv with 100% isodose, with the prescription dose of 45 gy in 1. 8 gy per fraction. Cheap viagra for sale C. Imrt planning for imrt, all of the treatment planning was performed by an experienced dosimetrist at ucsd. cheap generic viagra For each patient, 6 mv, eight-field, non-equidistant, coplanar, sliding-window imrt technique was planned on the eclipse treatment planning system (tps) (varian medical systems, paloalto, ca). The beam placement and dose-volume constraints were selected, monitored and interactively adjusted to best spare the pbm while maintaining adequate target coverage. Table 1 lists the planning goals used for general guidance of both imrt and proton therapy planning. cheap generic viagra Figure 1(a) illustrates the typical dose distribution achieved by this imrt technique. Table 1. â€‚ general planning guideline used for both intensity-modulated radiation therapy and 3d conformal proton therapy plan design. delivery overnight viagra â â fig. 1. cheap generic viagra â€‚ axial computed tomography image with isodose distribution from (a) intensity modulated radiation therapy plan, and (b) 3d conformal proton therapy plan. low price viagra Highlighted in green is the planning target volume. â d. Proton planning for 3dcpt, all of the treatment planning was performed by an experienced planning physicist at the university of florida proton therapy institute (ufpti). For each patient, two posterior oblique, and one anterior-inferior oblique (with 90â° couch kick) fields were planned on the eclipse tps with proton planning module. This three-field technique was chosen, after evaluating multiple different beam orientations, due to the following three reasons: 1) best minimized the pbm dose while achieving excellent target coverage (that is, lateral fields are detrimental to the pbm sparing, while ap/pa-type fields are the best), 2) anterior field with couch kick largely misses the bowel and also it is less prone to day-to-day variation in its proton beam path length due to the daily abdominal content change, and 3) two posterior oblique fieldsâ€™ axes align with the ilium curvature, thus minimizing dose to this structure and hence the total pbm dose. Figure 1(b) illustrates the typical dose distribution achieved by this 3dcpt technique. In terms of the proton beam delivery technique, the uniform scanning with aperture and range compensator was used. cheap viagra overnight delivery This technique can deliver a maximum water equivalent thickness (wet) range of 28 cm and 250 mm diameter field size. In ad.
Main features include:
Instrument to control & display the temperature of the liquid which circulates in a closed loop system.
Connecting hose & head piece with additional « nape of neck » & « collar » attachments for enhanced cooling/heating.
Cooling: liquid temperature cools from ambient to +3°C.
Heating: optional liquid heating.
Temperature controller: P.I.D control provides accurate temperature regulation of the circulating liquid and can display either as °C or °F
Patient temperature: a separate display permits the continuous monitoring of the patient's aural membrane temperature.
Power: operates from
Rechargeable batteries for approx. 60mins
12V paramedic vehicle.
Mains power 110/220V with suitable adaptor.
Nasal cannula: this option permits the introduction of chilled or heated air via the nostrils.
This versatile instrument with cooling/heating utilises « snap fit » connectors which facilitates interchangeable and easily detachable pads which can be applied to different body parts (extending the closed loop) to: